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CS-W001157 4
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(2S,3S)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol)

  • CAS No. 123287-35-4

  • Cat. No. CS-0086939
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2S,3S)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol)|CS-0086939

Structure of 123287-35-4

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Description

This spirocyclic diol features a rigid, electron-rich scaffold with two diphenylmethyl-protected hydroxyl groups. The (2S,3S) stereochemistry ensures predictable stereoselective reactivity in asymmetric synthesis, while the dioxaspiro core provides exceptional bench stability and moisture tolerance. Ideal for constructing complex molecular architectures in medicinal chemistry and natural product synthesis.

Application

(2S,3S)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol) serves as a rigid, chiral bis-protecting group scaffold enabling stereoselective transformations in complex molecule synthesis. Its spirocyclic architecture provides enhanced stability and orthogonal reactivity, facilitating efficient functionalization and purification in multi-step synthetic sequences. The diphenylmethyl (benzhydryl) moieties offer robust protection for diols and amines under standard conditions, while the defined stereochemistry supports asymmetric synthesis workflows.

General Information

  • CAS No. 123287-35-4
  • Cat. No. CS-0086939
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₄H₃₄O₄
  • Molecular Weight 506.63
  • Synonym(s) (2S,3S)-α2,α2,α3,α3-tetraphenyl-1,4-Dioxaspiro[4.5]decane-2,3-diMethanol
  • SMILES OC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@@H]3[C@@H](C(C4=CC=CC=C4)(C5=CC=CC=C5)O)OC6(CCCCC6)O3

Computational Chemistry Data

  • TPSA   58.92
  • LogP   6.303
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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