Lot numbers can be found on the outside label of a product:
tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate
-
CAS No. 270912-72-6
- Cat. No. CS-D0664
- Purity≥98%
- MDL No.MFCD01861798
*For research and further manufacturing use only, not for direct human use.
Structure of 270912-72-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 270912-72-6
- Cat. No. CS-D0664
- Purity ≥98%
- MDL No. MFCD01861798
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₂₀N₂O₂
- Molecular Weight 200.28
- Synonym(s) 1-Boc-3-(aminomethyl)-pyrrolidine
- SMILES O=C(N1CC(CN)CC1)OC(C)(C)C
Description
tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate delivers a protected amine functionality with enhanced solubility and stability under standard conditions. The pyrrolidine core integrates readily into complex molecular architectures, while the tert-butyl ester group enables straightforward deprotection. This scaffold serves as a key intermediate in medicinal chemistry for accessing bioactive heterocycles.
Application
tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling the efficient construction of pyrrolidine-containing scaffolds. The protected amine and pendant aldehyde functionality facilitate reductive amination, coupling reactions, and cyclization protocols. Its bench-stable tert-butyl carbamate group simplifies purification and allows orthogonal deprotection, making it well-suited for iterative synthesis workflows.
Synthesis
-
Route1
-
In-stock
24424-99-5 -
67318-88-1 - ~82%
-
In-stock
270912-72-6
References
-
Syntex (U.S.A.) Inc. Patent: US6166015 A1, 2000 ; US 6166015 A
-
-
Route2
-
1301188-94-2 - ~%
-
In-stock
270912-72-6
References
-
GLAXOSMITHKLINE LLC; DOCK, Steven, Thomas; MCSHERRY, Allison, K.; MOORE, Michael, Lee; RIDGERS, Lance, Howard; PARRISH, Cynthia, Ann Patent: WO2013/28445 A1, 2013 ; Location in patent: Page/Page column 50 ;
-
-
Route3
-
In-stock
114214-69-6 - ~%
-
In-stock
270912-72-6
References
-
MANNKIND CORPORATION; TOLERO PHARMACEUTICALS, INC.; ZENG, Qingping; FARIS, Mary; MOLLARD, Alexis; WARNER, Steven L.; FLYNN, Gary A. Patent: WO2014/52365 A1, 2014 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07,GHS09
|
|
Signal Word : Warning
|
UN#: 3082
|
|
Class : 9
|
Packing Group : Ⅲ
|
|
Hazard Statements : H302-H319-H410
|
|
|
Precautionary Statements : P264-P270-P273-P280-P330-P391-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 55.56
- LogP 1.2021
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 270912-72-6 sigma270912-72-6 manufacturer270912-72-6 price270912-72-6 structure270912-72-6 SDSbuy 270912-72-6270912-72-6 supplier270912-72-6 uses270912-72-6 molecular weightprice of 270912-72-6270912-72-6 chemical name formula of 270912-72-6