Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate

  • CAS No. 1235451-38-3

  • Cat. No. CS-W022961
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate|CS-W022961

Structure of 1235451-38-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1235451-38-3
  • Cat. No. CS-W022961
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄BrN₃O₂
  • Molecular Weight 288.14
  • Synonym(s) N-Boc-5-Bromo-2-pyrimidinemethanamine
  • SMILES O=C(OC(C)(C)C)NCC1=NC=C(Br)C=N1

Description

tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate delivers a brominated pyrimidine scaffold with a readily cleavable carbamate protecting group. This reagent enables direct functionalization at the 5-position of pyrimidine rings, facilitating late-stage diversification in medicinal chemistry. The tert-butyl carbamate moiety ensures stability during synthesis and purification, while the bromine atom provides a reactive handle for cross-coupling transformations.

Application

tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate serves as a versatile building block for the synthesis of brominated pyrimidine derivatives, enabling straightforward functionalization at the 5-position. The Boc-protected amine facilitates orthogonal handling in multi-step sequences, while the bromide acts as a reliable coupling handle in palladium-catalyzed transformations. Its bench stability and compatibility with standard reaction conditions make it ideal for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   64.11
  • LogP   2.2638
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1235451-38-3 sigma1235451-38-3 manufacturer1235451-38-3 price1235451-38-3 structure1235451-38-3 SDSbuy 1235451-38-31235451-38-3 supplier1235451-38-3 uses1235451-38-3 molecular weightprice of 1235451-38-31235451-38-3 chemical name formula of 1235451-38-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label