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Structure of 1239648-74-8
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8-Methyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine is a bench-stable heterocyclic amine featuring a fused triazolopyridine core with a methyl group at the 8-position. This electron-rich scaffold integrates readily into medicinal chemistry libraries, offering enhanced solubility and metabolic stability. The para-amino functionality enables direct coupling in Suzuki-Miyaura and Buchwald-Hartwig reactions, streamlining access to functionalized derivatives for drug discovery applications.
8-Methyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its robust pyridine-triazole fusion offers enhanced metabolic stability and favorable π-stacking interactions. The amine functionality facilitates direct derivatization via coupling reactions, while the methyl group provides steric and electronic modulation. Bench-stable and compatible with standard purification methods, it functions effectively in parallel synthesis campaigns and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: