6-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hexanamine

Name: 6-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hexanamine
Brand: ChemScene
Availability: InStock
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CAS No. 124883-99-4
Cat. No. CS-0645785
Purity≥95%
MDL No.MFCD23378731

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hexanamine|CS-0645785

Structure of 124883-99-4

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Description

6-[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hexanamine features a silyl-protected hydroxyl group paired with a terminal amine, enabling orthogonal functionalization in synthetic workflows. The bulky tert-butyldimethylsilyl moiety ensures high stability against protic and basic conditions, while the aliphatic chain facilitates solubility and compatibility with diverse reaction environments. This compound serves as a key building block for tailored molecular architectures in organic synthesis and materials development.

Application

6-[[[1,1-Dimethylethyl]dimethylsilyl]oxy]-1-hexanamine serves as a stable, bench-ready silyl-protected alcohol precursor, enabling reliable installation and orthogonal deprotection in complex synthesis. Its bulky tert-butyldimethylsilyl (TBS) group provides excellent stability toward nucleophiles and mild acidic conditions, facilitating selective functionalization at other sites. The primary amine functionality allows for further derivatization, making it a valuable building block for peptide analogs, macrocyclic scaffolds, and functionalized polymers.

General Information

CAS No. 124883-99-4
Cat. No. CS-0645785
Purity ≥95%
MDL No. MFCD23378731
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₉NOSi
Molecular Weight 231.46
Synonym(s) None
SMILES O(CCCCCCN)[Si](C)(C)C(C)(C)C

Computational Chemistry Data

TPSA 35.25
LogP 3.5273
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Other Classifications

Building Blocks Functional Group Organosilicon compounds

Building Blocks Skeleton Fatty chain compounds

Key Words

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6-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-1-hexanamine

CAS No. 124883-99-4

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