(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)oct-7-enoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)oct-7-enoic acid
Brand: ChemScene
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CAS No. 1251904-51-4
Cat. No. CS-0100591
Purity≥98%
MDL No.MFCD03094929

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)oct-7-enoic acid|CS-0100591

Structure of 1251904-51-4

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Description

This fluorenylmethoxycarbonyl-protected amino acid features a terminal alkene for downstream functionalization, offering enhanced stability and compatibility in peptide synthesis. The (S)-configuration ensures stereochemical fidelity in chiral building blocks.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)oct-7-enoic acid serves as a valuable chiral building block for peptide synthesis, enabling efficient incorporation of unsaturated amino acid motifs. The Fmoc group provides excellent stability and orthogonal deprotection under mild basic conditions, while the terminal alkene supports downstream functionalization via metathesis or hydrogenation. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for solid-phase and solution-phase peptide assembly.

General Information

CAS No. 1251904-51-4
Cat. No. CS-0100591
Purity ≥98%
MDL No. MFCD03094929
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₅NO₄
Molecular Weight 379.45
Synonym(s) (S)-N-FMoc-2-(5'-pentenyl)glycine
SMILES C=CCCCC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(O)=O

Computational Chemistry Data

TPSA 75.63
LogP 4.7247
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 9

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)oct-7-enoic acid

CAS No. 1251904-51-4

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