5'-Bromospiro[cyclopropane-1,3'-indoline]

Name: 5'-Bromospiro[cyclopropane-1,3'-indoline]
Brand: ChemScene
Availability: InStock
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CAS No. 1260763-03-8
Cat. No. CS-W022340
Purity≥96%
MDL No.MFCD13195331

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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5'-Bromospiro[cyclopropane-1,3'-indoline]|CS-W022340

Structure of 1260763-03-8

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Description

5'-Bromospiro[cyclopropane-1,3'-indoline] features a rigid spirocyclic framework with a bromine atom at the 5' position, enabling direct functionalization in transition-metal-catalyzed couplings. The cyclopropane ring imparts high strain energy, while the indoline moiety provides a stable, electron-rich heterocyclic platform. This scaffold serves as a key building block for complex alkaloid synthesis and medicinal chemistry libraries.

Application

5'-Bromospiro[cyclopropane-1,3'-indoline] serves as a versatile building block for constructing spirocyclic indoline architectures common in bioactive molecules. The bromine atom enables palladium-catalyzed cross-coupling reactions with broad functional group tolerance, facilitating rapid diversification. Its stable spirocyclic framework supports efficient synthesis of complex heterocycles, offering excellent bench stability and straightforward purification—ideal for medicinal chemistry and process development workflows.

General Information

CAS No. 1260763-03-8
Cat. No. CS-W022340
Purity ≥96%
MDL No. MFCD13195331
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₀BrN
Molecular Weight 224.10
Synonym(s) None
SMILES BrC1=CC(C23CC2)=C(NC3)C=C1

Computational Chemistry Data

TPSA 12.03
LogP 2.9062
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indolin compounds

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Building Blocks Skeleton Spirol Rings compounds

Key Words

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5'-Bromospiro[cyclopropane-1,3'-indoline]

CAS No. 1260763-03-8

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