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Structure of 1261764-39-9
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2-Methyl-3-(trifluoromethoxy)benzoic acid features a trifluoromethoxy group that imparts enhanced electron-withdrawal and metabolic stability, while the methyl substituent introduces steric bulk. This combination enhances lipophilicity and resistance to oxidative degradation. The carboxylic acid moiety enables direct derivatization for pharmaceutical intermediates and bioconjugation applications under standard conditions.
2-Methyl-3-(trifluoromethoxy)benzoic acid serves as a versatile building block for medicinal chemistry and agrochemical synthesis, offering a robust trifluoromethoxy group adjacent to a carboxylic acid and methyl substituent. Its stability under standard reaction conditions enables reliable coupling, derivatization, and heterocycle formation in multistep syntheses. The molecule functions effectively in amide bond construction, Suzuki-Miyaura cross-coupling, and as a scaffold for bioactive compound development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: