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Structure of 1261861-91-9
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2-Fluoro-3-(hydroxymethyl)benzonitrile features a strategically positioned fluorine atom and a hydroxymethyl group on a benzene ring bearing a nitrile functionality. This combination enables direct incorporation into pharmaceutical intermediates, offering enhanced metabolic stability and targeted reactivity for C–C bond formation under standard conditions.
2-Fluoro-3-(hydroxymethyl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds. The nitrile group facilitates nucleophilic addition and cyclization reactions, while the hydroxymethyl functionality supports oxidation to carboxylic acid or protection for subsequent transformations. Bench-stable and compatible with standard synthetic workflows, it offers reliable functional group tolerance and ease of purification in multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: