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Structure of 1282518-60-8
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This boronate ester integrates a sterically hindered isopropyl group and a stable tetramethyl-1,3,2-dioxaborolane moiety, enabling reliable cross-coupling under standard conditions. The pyrazole scaffold provides a rigid, electron-rich platform for modular derivatization in medicinal chemistry and materials science applications.
1-(1-Methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. Its pyrazole core provides excellent functional group tolerance and orthogonal reactivity, enabling efficient construction of biologically relevant heterocyclic scaffolds. The tetramethyl-substituted dioxaborolane moiety ensures high stability, minimal protodeboronation, and compatibility with diverse reaction conditions, facilitating straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: