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Structure of 128446-35-5
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(2-Hydroxypropyl)--cyclodextrin (HP--CD) is a beta-cyclodextrin and hydroxyalkyl derivative and is widely used as a chiral solvent, phase transfer catalyst, and host molecule in organic synthesis. HP--CD can form inclusion complexes with guest molecules, which can help enhance the solubility, stability, and bioavailability of the guest molecule. It is an alternative to -, - and -cyclodextrin and exhibits a higher water solubility. HP--CD is commonly used as a drug solubilizer.HP--CD can be used: As an additive in the separation of amino acids and lactic acids based on the coordination interactions between Cu2+ ions and analytes. As a chiral selector in capillary electrophoresis, enabling the robust separation of diastereomeric derivatives of aspartic acid for analysis. As a reagent to improve water solubility and anti-proliferative activity of pyrazolo[3,4-d] pyrimidines. As formulation vehicle. It increases water solubility of the drug for successful delivery of medical agents to a biological system.To increase the solubility of ropivacaine (RVC) upon complexation, which in turn enhances the pharmacological activity of RVC.To increase the aqueous solubility of naproxen (NAP) in presence of polyvinylpyrrolidone (PVP).As a template in the synthesis of hollow spherical copper sulfide nanoparticle assemblies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: