3-Chloro-5-iodopyridin-4-amine

Name: 3-Chloro-5-iodopyridin-4-amine
Brand: ChemScene
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CAS No. 1300750-79-1
Cat. No. CS-0041405
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3-Chloro-5-iodopyridin-4-amine|CS-0041405

Structure of 1300750-79-1

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Description

3-Chloro-5-iodopyridin-4-amine features a pyridine core functionalized with chlorine at the 3-position and iodine at the 5-position, bearing a primary amine group at the 4-position. This electron-deficient heterocycle serves as a key scaffold for constructing bioactive molecules, enabling efficient cross-coupling reactions under standard conditions. The strategic placement of halogens facilitates sequential transformations in medicinal chemistry and materials synthesis.

Application

3-Chloro-5-iodopyridin-4-amine serves as a versatile building block for the construction of functionalized pyridine scaffolds in medicinal chemistry and agrochemical research. Its orthogonal halogen reactivity enables sequential cross-coupling processes, facilitating efficient access to diverse biaryl and heterocyclic architectures. The compound exhibits good bench stability and compatibility with standard Pd-catalyzed coupling protocols, supporting reliable purification and scalable synthesis in complex molecule assembly.

General Information

CAS No. 1300750-79-1
Cat. No. CS-0041405
Purity ≥98%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄ClIN₂
Molecular Weight 254.46
Synonym(s) 3-chloro-5-iodo-4-Pyridinamine
SMILES NC1=C(Cl)C=NC=C1I

Computational Chemistry Data

TPSA 38.91
LogP 1.9218
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Chloro-5-iodopyridin-4-amine

CAS No. 1300750-79-1

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