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Structure of 1303968-07-1
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2-Azaspiro[3.5]nonane hydrochloride is a rigid, bicyclic amine scaffold featuring a spiro-configured nitrogen atom at the bridgehead. This structural motif imparts enhanced conformational stability and favorable solubility in polar solvents. The hydrochloride salt form ensures excellent crystallinity and shelf stability under ambient conditions. It serves as a key building block in medicinal chemistry for probing bioactive conformations in target-directed ligands.
2-Azaspiro[3.5]nonane hydrochloride serves as a conformationally constrained, nitrogen-containing heterocyclic scaffold widely employed in medicinal chemistry for its ability to stabilize bioactive conformations. The spirocyclic structure imparts rigidity, enhancing target selectivity and metabolic stability. As a readily accessible building block, it facilitates the synthesis of complex alkaloids and pharmaceutically relevant scaffolds through standard functionalization and coupling reactions. Its salt form ensures improved solubility and handling in aqueous-based reaction systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: