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Structure of 1314893-97-4
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3-Bromopyrazolo[1,5-a]pyrimidin-6-ol features a brominated pyrazolo[1,5-a]pyrimidine core with a phenolic hydroxyl group, enabling direct functionalization in medicinal chemistry. This scaffold integrates readily into kinase inhibitors and nucleoside analogs due to its planar structure and hydrogen-bonding capacity. The bromine atom serves as a handle for palladium-catalyzed cross-coupling reactions under standard conditions.
3-Bromopyrazolo[1,5-a]pyrimidin-6-ol serves as a versatile heterocyclic building block for medicinal chemistry and catalytic cross-coupling applications. Its bromine substituent enables palladium-catalyzed transformations such as Suzuki-Miyaura and Buchwald-Hartwig couplings, while the pyrimidin-6-ol functionality offers hydrogen-bonding capacity and metabolic stability. The compound exhibits good bench stability and facilitates efficient purification via crystallization or chromatography, making it well-suited for scalable synthesis of kinase inhibitors and other bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: