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Structure of 13412-12-9
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Methyl 3-methylaminocrotonate is a versatile β-amino acrylate ester featuring a conjugated enone system and a tertiary amine group. This structure enables efficient Michael additions and serves as a key intermediate in synthesizing bioactive heterocycles, particularly in medicinal chemistry applications. The molecule exhibits enhanced reactivity due to the electron-donating methylamino substituent adjacent to the electrophilic β-carbon.
Methyl 3-methylaminocrotonate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyrrolidines and other nitrogen-containing heterocycles via cyclization reactions. Its conjugated enamine system facilitates Michael additions and [4+2] cycloadditions, while the ester group allows for selective transformations under mild conditions. Bench-stable and amenable to purification by standard chromatography, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: