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CS-W001157 4
Total: USD 88.00

Methyl 3-methylaminocrotonate

  • CAS No. 13412-12-9

  • Cat. No. CS-M1728
  • Purity≥98%
  • MDL No.MFCD00027383
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 3-methylaminocrotonate|CS-M1728

Structure of 13412-12-9

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Description

Methyl 3-methylaminocrotonate is a versatile β-amino acrylate ester featuring a conjugated enone system and a tertiary amine group. This structure enables efficient Michael additions and serves as a key intermediate in synthesizing bioactive heterocycles, particularly in medicinal chemistry applications. The molecule exhibits enhanced reactivity due to the electron-donating methylamino substituent adjacent to the electrophilic β-carbon.

Application

Methyl 3-methylaminocrotonate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyrrolidines and other nitrogen-containing heterocycles via cyclization reactions. Its conjugated enamine system facilitates Michael additions and [4+2] cycloadditions, while the ester group allows for selective transformations under mild conditions. Bench-stable and amenable to purification by standard chromatography, it functions reliably in multi-step syntheses requiring functional group tolerance and predictable reactivity.

General Information

  • CAS No. 13412-12-9
  • Cat. No. CS-M1728
  • Purity ≥98%
  • MDL No. MFCD00027383
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) Methyl 3-(methylamino)but-2-enoate
  • SMILES C/C(NC)=C\C(OC)=O

Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.2826
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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