7-Amino-2,3-dihydrobenzofuran

Name: 7-Amino-2,3-dihydrobenzofuran
Brand: ChemScene
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CAS No. 13414-56-7
Cat. No. CS-B1184
Purity≥98%
MDL No.MFCD11109313

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 13414-56-7

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Description

7-Amino-2,3-dihydrobenzofuran is a heterocyclic scaffold featuring a fused benzene and tetrahydrofuran ring system with a primary amine at the 7-position. This electron-rich moiety serves as a key building block in medicinal chemistry, enabling direct incorporation into bioactive molecules through nucleophilic coupling reactions. The compound exhibits favorable solubility and stability under standard bench conditions, facilitating its use in synthetic workflows targeting CNS agents and kinase inhibitors.

Application

7-Amino-2,3-dihydrobenzofuran serves as a versatile building block in medicinal chemistry, enabling direct access to bioactive heterocycles through standard functionalization. Its electron-rich aromatic core and amine functionality facilitate coupling reactions, electrophilic substitutions, and derivatization under mild conditions. Bench-stable and readily purified, it functions effectively in the synthesis of pharmaceutical intermediates and targeted scaffolds.

General Information

CAS No. 13414-56-7
Cat. No. CS-B1184
Purity ≥98%
MDL No. MFCD11109313
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉NO
Molecular Weight 135.16
Synonym(s) (2,3-Dihydrobenzofuran-7-yl)amine; 2,3-Dihydro-7-benzofuranamine; 7-Benzofuranamine, 2,3-dihydro-
SMILES NC1=C(OCC2)C2=CC=C1

Computational Chemistry Data

TPSA 35.25
LogP 1.2037
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Benzofuran compounds

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7-Amino-2,3-dihydrobenzofuran

CAS No. 13414-56-7

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