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Structure of 153898-63-6
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2-Iodo-5-methoxybenzenamine features a methoxy group at the para position relative to the amine, enhancing electron density and solubility. The iodine substituent enables efficient cross-coupling reactions under standard conditions. This bench-stable aryl amine serves as a key intermediate in pharmaceutical synthesis, particularly for targeted heterocyclic systems requiring precise substitution patterns.
2-Iodo-5-methoxybenzenamine serves as a versatile building block for constructing substituted anilines and heterocyclic scaffolds in medicinal chemistry. Its iodine group enables reliable Suzuki, Stille, and Negishi coupling reactions, while the methoxy and amine functionalities offer orthogonal reactivity for sequential modifications. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: