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CS-W001157 4
Total: USD 88.00

5-Fluoro-4-iodopyridin-3-amine

  • CAS No. 1350475-29-4

  • Cat. No. CS-0146700
  • Purity≥97%
  • MDL No.MFCD21362312

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-4-iodopyridin-3-amine|CS-0146700

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General Information

  • CAS No. 1350475-29-4
  • Cat. No. CS-0146700
  • Purity ≥97%
  • MDL No. MFCD21362312
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄FIN₂
  • Molecular Weight 238.00
  • Synonym(s) 5-Fluoro-4-Iodo-Pyridin-3-Ylamine
  • SMILES NC1=C(I)C(F)=CN=C1

Description

5-Fluoro-4-iodopyridin-3-amine features a trifunctional pyridine core bearing fluorine, iodine, and amino groups at strategic positions. This configuration enables direct incorporation into cross-coupling reactions, serving as a key building block for bioactive heterocycles in medicinal chemistry and materials science.

Application

5-Fluoro-4-iodopyridin-3-amine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to biologically relevant pyridine scaffolds. The iodine group facilitates reliable palladium-catalyzed coupling reactions, while the fluorine and amine functionalities offer orthogonal reactivity for downstream modifications. This compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for medicinal chemistry campaigns and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.4075
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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