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Structure of 135242-71-6
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3-Hydroxy-4-iodobenzaldehyde features a hydroxyl group adjacent to an electron-deficient aldehyde, paired with a para-iodo substituent that enables facile cross-coupling. This combination delivers enhanced reactivity in Suzuki and Sonogashira reactions while maintaining bench-stable handling under standard conditions.
3-Hydroxy-4-iodobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its iodine handle. The aldehyde group facilitates reductive amination or Wittig-type transformations, while the phenolic hydroxyl supports derivatization and metal coordination. Its bench-stable nature and compatibility with common protecting group strategies make it well-suited for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: