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Structure of 1354290-88-2
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This boronate moiety features a difluoromethoxy-substituted pyridine core, delivering enhanced stability and solubility in polar solvents. The electron-deficient pyridine ring facilitates efficient Suzuki-Miyaura coupling, while the bench-stable boronic acid group enables reliable cross-coupling under standard conditions.
(6-(Difluoromethoxy)pyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The difluoromethoxy group imparts enhanced metabolic stability and modulates electronic properties, making this scaffold valuable for medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it exhibits broad functional group tolerance and compatibility with standard cross-coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: