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Structure of 1355049-94-3
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This tetrahydrofuran derivative features a pyrrolo[2,1-f][1,2,4]triazine core functionalized with a primary amine and multiple benzyl-protected hydroxyl groups. The stereochemistry at the 3r,4r,5r positions confers high diastereoselectivity in downstream transformations. Designed for use in medicinal chemistry campaigns targeting kinase inhibitors and nucleoside analogs, this scaffold integrates readily into complex molecular architectures under standard coupling conditions.
(3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dibenzyloxy-5-(benzyloxymethyl)tetrahydrofuran-2-ol serves as a stereochemically defined glycosyl building block for nucleoside analog synthesis. The triazine-amino functionality enables efficient coupling in late-stage diversification, while the protected hydroxyl groups offer orthogonal handling and stability under standard reaction conditions. Its bench-stable, crystalline nature facilitates purification and integration into iterative synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: