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Structure of 1356113-07-9
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4-Bromo-3-fluoro-5-methylaniline features a strategically positioned bromo and fluoro substituent flanking a methylated aniline core, enabling selective coupling reactions in pharmaceutical synthesis. This electron-deficient aromatic amine integrates readily into complex scaffolds under standard conditions, offering enhanced reactivity and stability for advanced intermediate construction.
4-Bromo-3-fluoro-5-methylaniline serves as a valuable building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its ortho-substituted arylamine framework enables reliable coupling reactions, while the bromo and fluoro groups provide orthogonal handles for further derivatization via palladium-catalyzed cross-coupling or nucleophilic substitution. The methyl group enhances metabolic stability and modulates electronic properties, offering predictable reactivity in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: