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Structure of 13600-47-0
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5-Aminonicotinonitrile features a bifunctional scaffold combining an electron-rich amine and a strongly electron-deficient nitrile group. This arrangement enables direct incorporation into diverse heterocyclic systems via nucleophilic addition or coupling reactions. The molecule exhibits robust bench stability and compatibility with standard synthetic protocols, facilitating efficient access to functionalized pyridine derivatives for medicinal chemistry applications.
5-Aminonicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of pyridine-based heterocycles and bioactive scaffolds. Its dual functionality—amine and nitrile groups—supports diverse transformations including amidation, cyclization, and metal-catalyzed coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: