6-Bromo-1H-indazol-5-amine

Name: 6-Bromo-1H-indazol-5-amine
Brand: ChemScene
Availability: InStock
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CAS No. 1360928-41-1
Cat. No. CS-0050315
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 1360928-41-1

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Description

6-Bromo-1H-indazol-5-amine features a brominated indazole core with a primary amine at the 5-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient heterocycle integrates readily into bioactive scaffolds and serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and CNS modulators.

Application

6-Bromo-1H-indazol-5-amine serves as a versatile building block for the synthesis of biologically active heterocycles, enabling direct functionalization at the indazole core. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, while the primary amine supports derivatization via acylation, alkylation, or cyclization. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for medicinal chemistry campaigns and process-scale applications.

General Information

CAS No. 1360928-41-1
Cat. No. CS-0050315
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆BrN₃
Molecular Weight 212.05
Synonym(s) 6-Bromo-1H-indazol-5-ylamine
SMILES NC1=CC2=C(NN=C2)C=C1Br

Computational Chemistry Data

TPSA 54.7
LogP 1.9076
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Indazole compounds

Key Words

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6-Bromo-1H-indazol-5-amine

CAS No. 1360928-41-1

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