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Structure of 1367970-52-2
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This trifluoromethyl-substituted pyrimidinone integrates a reactive ketone group and electron-deficient heterocyclic core, enabling direct incorporation into medicinal chemistry scaffolds. The trifluoromethyl moiety enhances metabolic stability and membrane permeability, while the bench-stable ketone facilitates nucleophilic addition or reductive functionalization under standard conditions.
1-(2-(Trifluoromethyl)pyrimidin-5-yl)ethan-1-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the acetyl functionality facilitates nucleophilic substitution and coupling reactions. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for use in multi-step synthesis and API development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H302-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: