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Structure of 304693-66-1
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2-(Trifluoromethyl)pyrimidine-5-carbaldehyde features a trifluoromethyl group at the 2-position and a formyl group at the 5-position on a pyrimidine core. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and favorable lipophilicity for target engagement.
2-(Trifluoromethyl)pyrimidine-5-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functional group transformations. Its electrophilic aldehyde moiety facilitates nucleophilic additions and condensations, while the electron-deficient trifluoromethylpyrimidine core enhances metabolic stability and modulates physicochemical properties. The compound exhibits excellent bench stability and compatibility with common reaction conditions, supporting efficient synthesis of pharmaceutical intermediates and API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: