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*For research and further manufacturing use only, not for direct human use.
Structure of 13720-52-0
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8-Fluoronaphthalen-1-amine features a fluorinated naphthalene core with an amino group at the 1-position, delivering enhanced electron-donating character and improved metabolic stability. This combination enables efficient coupling in cross-coupling reactions and facilitates incorporation into functional materials.
8-Fluoronaphthalen-1-amine serves as a valuable building block for the synthesis of functionalized naphthalene derivatives, enabling direct incorporation of both amine and fluorine functionalities in a single scaffold. Its reactivity is well-suited for Suzuki-Miyaura coupling, electrophilic substitution, and amide bond formation, with the fluorine substituent providing orthogonal reactivity and enhanced metabolic stability. The compound exhibits good bench stability and facilitates straightforward purification, making it ideal for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: