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Structure of 1374258-63-5
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6-Bromo-3-(trifluoromethyl)-1H-indazole is a sterically hindered, electron-deficient heterocycle featuring a bromine at the 6-position and a trifluoromethyl group at the 3-position. This combination enhances metabolic stability and facilitates downstream functionalization via cross-coupling reactions. The molecule exhibits excellent bench-stability and solubility in common organic solvents, enabling seamless integration into medicinal chemistry and materials synthesis workflows.
6-Bromo-3-(trifluoromethyl)-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine handle and electron-deficient indazole core. The trifluoromethyl group enhances metabolic stability and modulates lipophilicity, while the compound exhibits good bench stability and compatibility with standard purification methods. It functions effectively in the synthesis of heterocyclic scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: