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Structure of 1374666-32-6
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Mal-PEG2-acid features a maleimide group conjugated to a short PEG2 spacer terminating in a carboxylic acid. This bifunctional architecture enables site-specific bioconjugation via thiol-Michael addition, followed by facile coupling to amine-containing biomolecules under standard conditions. The PEG2 linker imparts enhanced solubility and reduced aggregation, improving handling in aqueous environments.
Mal-PEG2-acid serves as a versatile bifunctional linker for conjugation and bioconjugation workflows. The maleimide group enables site-specific, thiol-selective coupling under physiological conditions, while the terminal carboxylic acid facilitates amine-based conjugation or further derivatization. PEG2 spacer provides enhanced solubility and reduced steric hindrance, improving reactivity and stability in aqueous environments. Ideal for antibody-drug conjugates, peptide modifications, and surface functionalization.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501
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Lot numbers can be found on the outside label of a product: