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Structure of 137731-41-0
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rel-(1R,2R)-N-Boc-1,2-cyclohexanediamine is a stereochemically defined diamine scaffold featuring a bulky Boc-protecting group on one nitrogen. This configuration imparts enhanced stability and selective reactivity in asymmetric synthesis. The molecule integrates readily into chiral ligand design and catalyst development, offering predictable stereocontrol in transition metal-catalyzed transformations.
rel-(1R,2R)-N-Boc-1,2-cyclohexanediamine serves as a stereochemically defined chiral auxiliary for asymmetric synthesis, enabling efficient construction of enantioselective catalysts and bioactive heterocycles. The Boc group provides excellent bench stability and orthogonal protection, facilitating straightforward deprotection under mild acidic conditions. Its rigid cyclohexane backbone enhances diastereoselectivity in C–N bond-forming reactions, while tolerating diverse functional groups—making it a reliable building block in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: