Lenalidomide-OH

Name: Lenalidomide-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1416990-08-3
Cat. No. CS-0112251
Purity≥95%
MDL No.MFCD31794971

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1416990-08-3

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Description

Lenalidomide-OH features a hydroxyl-modified imide scaffold that enhances solubility and metabolic stability compared to parent lenalidomide. This derivative integrates readily into targeted protein degradation workflows, offering improved handling under standard bench conditions while maintaining potent immunomodulatory activity.

Application

Lenalidomide-OH serves as a key synthetic intermediate for immunomodulatory drug derivatives, enabling straightforward access to the thalidomide scaffold. Its hydroxyl functionality enhances solubility and provides a handle for further functionalization via esterification or coupling reactions. The compound exhibits bench stability and compatibility with standard peptide and heterocyclic synthesis protocols, facilitating efficient route development in medicinal chemistry campaigns targeting hematological malignancies.

General Information

CAS No. 1416990-08-3
Cat. No. CS-0112251
Purity ≥95%
MDL No. MFCD31794971
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₂N₂O₄
Molecular Weight 260.25
Synonym(s) None
SMILES O=C(C(N(CC1=C2C=CC(O)=C1)C2=O)CC3)NC3=O

Computational Chemistry Data

TPSA 86.71
LogP -0.4067
H_Acceptors 6
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Other Classifications

Life Science PROTAC Ligands for E3 Ligase

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Lenalidomide-OH

CAS No. 1416990-08-3

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