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CS-W001157 4
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2,6-Difluoro-4-iodoaniline

  • CAS No. 141743-49-9

  • Cat. No. CS-0063173
  • Purity≥97%
  • MDL No.MFCD07774189

*For research and further manufacturing use only, not for direct human use.

2,6-Difluoro-4-iodoaniline|CS-0063173

Structure of 141743-49-9

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General Information

  • CAS No. 141743-49-9
  • Cat. No. CS-0063173
  • Purity ≥97%
  • MDL No. MFCD07774189
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄F₂IN
  • Molecular Weight 255.00
  • Synonym(s) 2,6-Difluoro-4-iodobenzenamine
  • SMILES NC1=C(F)C=C(I)C=C1F

Description

2,6-Difluoro-4-iodoaniline features a trifunctional aromatic core with fluorine and iodine substituents positioned for selective coupling. The electron-deficient aryl ring enables efficient palladium-catalyzed cross-coupling reactions under standard conditions. This bench-stable compound integrates readily into complex molecular architectures requiring halogen-directed functionalization.

Synthesis

  • Route1

    References

    • Bleger, David; Schwarz, Jutta; Brouwer, Albert M.; Hecht, Stefan Journal of the American Chemical Society, 2012 , vol. 134, # 51 p. 20597 - 20600

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.1516
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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