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CS-W001157 4
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Methyl 2-(3-formylphenyl)acetate

  • CAS No. 142327-44-4

  • Cat. No. CS-0150712
  • Purity≥97%
  • MDL No.MFCD15523582

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(3-formylphenyl)acetate|CS-0150712

Structure of 142327-44-4

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General Information

  • CAS No. 142327-44-4
  • Cat. No. CS-0150712
  • Purity ≥97%
  • MDL No. MFCD15523582
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₃
  • Molecular Weight 178.18
  • Synonym(s) methyl 3-formylphenylacetate
  • SMILES COC(=O)CC1=CC(=CC=C1)C=O

Description

Methyl 2-(3-formylphenyl)acetate features a benzaldehyde moiety linked to an acetic acid ester, enabling direct integration into multistep synthesis. The ortho-formyl group facilitates cyclization and metal-catalyzed coupling reactions. This compound serves as a key intermediate in constructing complex heterocycles and bioactive scaffolds under standard conditions.

Application

Methyl 2-(3-formylphenyl)acetate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of biologically relevant scaffolds. The ortho-aldehyde and ester functionalities offer complementary reactivity for sequential transformations, including reductive amination, Wittig reactions, and condensation processes. Its bench-stable nature and compatibility with common protecting group strategies facilitate straightforward purification and integration into multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   1.2146
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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