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Structure of 1426520-69-5
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4-[4-[4-(Trifluoromethoxy)phenyl]-1-piperidinyl]benzenemethanamine is a structurally defined tertiary amine featuring a trifluoromethoxy-substituted aryl piperidine motif. This electron-rich scaffold integrates a flexible piperidine ring with a benzylamine handle, enabling targeted conjugation and molecular diversification in medicinal chemistry applications. The trifluoromethoxy group enhances lipophilicity and metabolic stability, while the overall architecture supports high-affinity binding in receptor-targeted drug discovery.
4-[4-[4-(Trifluoromethoxy)phenyl]-1-piperidinyl]benzenemethanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its piperidine core offers favorable solubility and metabolic stability, while the trifluoromethoxy group enhances lipophilicity and target binding affinity. The primary amine functions as a handle for conjugation or salt formation, facilitating purification and formulation. This compound demonstrates robust bench stability and compatibility with standard coupling reactions, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: