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CS-W001157 4
Total: USD 88.00

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate

  • CAS No. 1434141-69-1

  • Cat. No. CS-0048149
  • Purity≥96%
  • MDL No.MFCD27956901
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate|CS-0048149

Structure of 1434141-69-1

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Description

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate features a spirocyclic scaffold with a pendant hydroxymethyl group, enabling direct functionalization in synthetic routes. The tert-butyl ester provides stability and ease of removal under mild acidic conditions. This compound serves as a key intermediate in the synthesis of bioactive aza-spirocycles, particularly in medicinal chemistry applications requiring stereoselective access to complex nitrogen-containing ring systems.

Application

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry and natural product synthesis. The hydroxymethyl group enables selective oxidation to aldehyde or carboxylic acid, while the tert-butyl ester allows for mild deprotection under acidic conditions. Its rigid spiro framework provides defined stereochemistry and enhances metabolic stability, facilitating efficient access to complex nitrogen-containing scaffolds via standard functional group interconversions.

General Information

  • CAS No. 1434141-69-1
  • Cat. No. CS-0048149
  • Purity ≥96%
  • MDL No. MFCD27956901
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₅NO₃
  • Molecular Weight 255.36
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CC2(C1)CCC(CO)CC2

Computational Chemistry Data

  • TPSA   49.77
  • LogP   2.406
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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