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CS-W001157 4
Total: USD 88.00

4-Chloro-5,6-dimethylpyrimidin-2-amine

  • CAS No. 14394-61-7

  • Cat. No. CS-0045830
  • Molecule weight157.60
  • Purity≥97%
  • MDL No.MFCD00462111

*For research and further manufacturing use only, not for direct human use.

4-Chloro-5,6-dimethylpyrimidin-2-amine|CS-0045830

Structure of 14394-61-7

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General Information

  • CAS No. 14394-61-7
  • Cat. No. CS-0045830
  • Purity ≥97%
  • MDL No. MFCD00462111
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈ClN₃
  • Molecular Weight 157.60
  • Synonym(s) NSC 66053
  • SMILES NC1=NC(C)=C(C)C(Cl)=N1

Description

Azido-PEG9-acid is a PEG molecule consisting of an azide and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU).

Synthesis

  • Route1
    • null|null
      570415-47-3
    • ~43%
    • 4-Chloro-5,6-dimethylpyrimidin-2-amine|CS-0045830
      14394-61-7

    References

    • BAYER CORPORATION Patent: US2004/2508 A1, 2004 ; Location in patent: Page/Page column 10-11 ; US 20040002508 A1
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 69, p. 3072,3075
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 69, p. 3072,3075

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.32904
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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