Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

DMT-2'-F-iBu-G

  • CAS No. 144089-96-3

  • Cat. No. CS-0172983
  • Purity≥97%
  • MDL No.MFCD15145247

*For research and further manufacturing use only, not for direct human use.

DMT-2'-F-iBu-G|CS-0172983

Structure of 144089-96-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 144089-96-3
  • Cat. No. CS-0172983
  • Purity ≥97%
  • MDL No. MFCD15145247
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₅H₃₆FN₅O₇
  • Molecular Weight 657.69
  • Synonym(s) 5'-DMT-2'-F-ibu-dG
  • SMILES F[C@@H]1[C@H](O)[C@@H](COC(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4)O[C@H]1N(C=N5)C(NC(NC(C(C)C)=O)=N6)=C5C6=O

Description

DMT-2'-F-iBu-G delivers a sterically hindered, fluorinated nucleoside building block with enhanced stability and improved coupling efficiency in oligonucleotide synthesis. The 2'-fluoro isobutyl modification confers resistance to nuclease degradation while maintaining favorable hybridization properties. This protected phosphoramidite integrates seamlessly into automated workflows for therapeutic and diagnostic applications.

Application

DMT-2'-F-iBu-G serves as a protected nucleoside building block for the synthesis of modified oligonucleotides, featuring a 2'-fluoro substitution and isobutyl protection at the 3'-oxygen. The dimethoxytrityl (DMT) group enables efficient monitoring and purification during solid-phase synthesis. This derivative offers enhanced nuclease resistance and improved hybridization affinity, facilitating reliable incorporation into antisense and siRNA constructs with minimal side reactions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   149.82
  • LogP   4.3364
  • H_Acceptors   10
  • H_Donors   3
  • Rotatable_Bonds   11

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • DMT-2'-F-iBu-G sigmaDMT-2'-F-iBu-G manufacturerDMT-2'-F-iBu-G priceDMT-2'-F-iBu-G structureDMT-2'-F-iBu-G SDSbuy DMT-2'-F-iBu-GDMT-2'-F-iBu-G supplierDMT-2'-F-iBu-G usesDMT-2'-F-iBu-G molecular weightprice of DMT-2'-F-iBu-GDMT-2'-F-iBu-G chemical name formula of DMT-2'-F-iBu-G
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label