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Structure of 144208-62-8
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OTs-PEG1-NHCbz is a bench-stable, moisture-tolerant linker featuring a sulfonate ester handle and a PEG-1 spacer that connects to a carbamoyl-protected nitrogen heterocycle. This design enables efficient conjugation workflows in bioconjugation and probe synthesis, combining high reactivity with ease of handling under standard conditions.
OTs-PEG1-NHCbz serves as a versatile bifunctional linker for peptide and oligonucleotide conjugation, combining the stability of a tosyl (OTs) leaving group with the solubility and biocompatibility of a PEG1 spacer. The NHCbz (N-carbobenzyloxy) moiety enables selective deprotection under mild hydrogenolysis conditions, facilitating controlled release or further functionalization. This reagent facilitates efficient coupling in solid-phase synthesis and offers excellent handling characteristics, making it well-suited for applications in bioconjugate chemistry and targeted drug delivery systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: