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Structure of 192132-77-7
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Tos-PEG2-NH-Boc features a bis(tert-butoxycarbonyl)amino terminus linked via a short PEG spacer to a tosyl group, enabling dual protection for amine functionalities. This bifunctional reagent integrates seamlessly into peptide synthesis workflows, offering orthogonal handling and controlled deprotection under mild conditions.
Tos-PEG2-NH-Boc serves as a versatile bifunctional building block for peptide and oligonucleotide conjugation, combining a tosyl (Tos) leaving group with a PEG2 spacer and a Boc-protected amine. The Tos group enables efficient nucleophilic substitution with amines or thiols, while the PEG2 spacer enhances solubility and reduces aggregation. The Boc-protected amine offers orthogonal handling in multi-step syntheses, facilitating selective deprotection and coupling under standard conditions. This reagent supports reliable functionalization in solid-phase and solution-phase workflows.
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331-H341
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: