Dibromomaleimide-C5-COOH

Name: Dibromomaleimide-C5-COOH
Brand: ChemScene
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CAS No. 1443214-97-8
Cat. No. CS-0905379
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 1443214-97-8

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Description

Dibromomaleimide-C5-COOH is a bifunctional crosslinker featuring maleimide and carboxylic acid handles. The maleimide moiety selectively reacts with thiols under physiological conditions, while the C5 spacer provides optimal flexibility for conjugation. This derivative enables efficient bioconjugation in antibody-drug conjugates and peptide-protein labeling workflows.

Application

Dibromomaleimide-C5-COOH serves as a versatile bifunctional building block for the synthesis of conjugated polymers and bioconjugates. Its maleimide moiety enables efficient Michael addition with thiols under physiological conditions, while the C5-carboxylic acid facilitates coupling via amine-reactive esters or carbodiimide chemistry. The molecule exhibits good bench stability and compatibility with diverse functional groups, enabling modular assembly in peptide-drug conjugates and surface-functionalized materials.

General Information

CAS No. 1443214-97-8
Cat. No. CS-0905379
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₁Br₂NO₄
Molecular Weight 369.01
Synonym(s) DBM-C5-COOH
SMILES O=C(CCCCCN1C(C(Br)=C(C1=O)Br)=O)O

Computational Chemistry Data

TPSA N/A
LogP N/A
H_Acceptors N/A
H_Donors N/A
Rotatable_Bonds N/A

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Dibromomaleimide-C5-COOH

CAS No. 1443214-97-8

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