3-Bromo-2,4-dichloropyridine

Name: 3-Bromo-2,4-dichloropyridine
Brand: ChemScene
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CAS No. 144584-32-7
Cat. No. CS-W021852
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 144584-32-7
Cat. No. CS-W021852
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂BrCl₂N
Molecular Weight 226.89
Synonym(s) Pyridine, 3-bromo-2,4-dichloro-
SMILES ClC1=C(Br)C(Cl)=NC=C1

Description

3-Bromo-2,4-dichloropyridine is a halogenated pyridine derivative featuring strategically positioned bromo and dichloro substituents that enable selective cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering high reactivity under palladium-catalyzed conditions with excellent functional group tolerance.

Application

3-Bromo-2,4-dichloropyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The strategically positioned bromo and chloro substituents provide orthogonal reactivity for sequential transformations, while the pyridine core offers excellent stability and compatibility with diverse reaction conditions. Its bench-stable nature and ease of purification make it ideal for scalable synthesis workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 12.89
LogP 3.1509
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Bromo-2,4-dichloropyridine

CAS No. 144584-32-7

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