4-(4-Methylthiazol-5-yl)benzylamine

Name: 4-(4-Methylthiazol-5-yl)benzylamine
Brand: ChemScene
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CAS No. 1448189-30-7
Cat. No. CS-W021052
Purity≥95%
MDL No.MFCD28965258

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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4-(4-Methylthiazol-5-yl)benzylamine|CS-W021052

Structure of 1448189-30-7

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Description

4-(4-Methylthiazol-5-yl)benzylamine features a thiazole-anchored aromatic linker that enables efficient integration into bioactive scaffolds. The pendant amine group offers a versatile handle for conjugation, while the methyl-substituted thiazole enhances electron density and metabolic stability. This compound serves as a key intermediate in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active molecules.

Application

4-(4-Methylthiazol-5-yl)benzylamine serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry and agrochemical research. The molecule combines a thiazole ring with a benzylamine handle, enabling facile derivatization via amine-functionalized coupling reactions. Its bench-stable nature and compatibility with standard protection/deprotection protocols facilitate efficient access to diverse scaffold libraries.

General Information

CAS No. 1448189-30-7
Cat. No. CS-W021052
Purity ≥95%
MDL No. MFCD28965258
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₂N₂S
Molecular Weight None
Synonym(s) (4-(4-Methylthiazol-5-yl)phenyl)methanamine
SMILES NCC1=CC=C(C2=C(C)N=CS2)C=C1

Computational Chemistry Data

TPSA 38.91
LogP 2.57722
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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4-(4-Methylthiazol-5-yl)benzylamine

CAS No. 1448189-30-7

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