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Structure of 144851-82-1
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Methyl 2-amino-3-fluorobenzoate features a strategically positioned amino group flanked by fluorine and ester functionalities, enabling direct incorporation into bioactive scaffolds. This electron-rich heterocyclic derivative exhibits enhanced solubility in polar organic solvents and stability under standard bench conditions, facilitating efficient derivatization in medicinal chemistry campaigns.
Methyl 2-amino-3-fluorobenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds via standard condensation and cyclization protocols. The ortho-amino and fluorine substituents provide complementary reactivity for sequential functionalization, while the methyl ester group facilitates straightforward manipulation. Bench-stable and amenable to purification by recrystallization or flash chromatography, it supports scalable synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: