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Structure of 1448855-35-3
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tert-Butyl 3-bromo-1H-pyrazole-1-carboxylate is a bench-stable, moisture-tolerant building block featuring a brominated pyrazole core. This compound integrates readily into cross-coupling reactions, enabling efficient access to functionalized heterocycles. The tert-butyl ester group facilitates purification and subsequent deprotection under mild acidic conditions.
tert-Butyl 3-bromo-1H-pyrazole-1-carboxylate serves as a versatile building block for the synthesis of brominated pyrazole derivatives, enabling efficient late-stage functionalization in medicinal chemistry. Its stability under standard reaction conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate the construction of biologically relevant heterocyclic scaffolds. The tert-butyl carbamate group provides excellent solubility and ease of purification, while the bromine substituent offers a reliable handle for further diversification via Suzuki, Stille, or Negishi couplings.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: