2-Hydroxy-N,N-dimethylacetamide

Name: 2-Hydroxy-N,N-dimethylacetamide
Brand: ChemScene
Availability: InStock
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CAS No. 14658-93-6
Cat. No. CS-0077250
Purity≥98%
MDL No.MFCD12137922

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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2-Hydroxy-N,N-dimethylacetamide|CS-0077250

Structure of 14658-93-6

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Description

This hydroxyl-functionalized amide integrates seamlessly into synthetic workflows, offering enhanced solubility and stability under standard conditions. The dimethylamino group imparts favorable polarity, while the pendant hydroxyl enables downstream derivatization or hydrogen bonding in reaction systems.

Application

2-Hydroxy-N,N-dimethylacetamide serves as a stable, bench-ready synthon for hydroxyl-directed functionalization in medicinal chemistry and process development. Its amide functionality exhibits excellent compatibility with diverse reaction conditions, enabling efficient derivatization via esterification, activation, or substitution protocols. The molecule functions effectively as a protected hydroxyl surrogate in multi-step sequences, offering straightforward purification and predictable reactivity across standard synthetic workflows.

General Information

CAS No. 14658-93-6
Cat. No. CS-0077250
Purity ≥98%
MDL No. MFCD12137922
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₉NO₂
Molecular Weight 103.12
Synonym(s) N,N-dimethylglycolic amide
SMILES CN(C)C(CO)=O

Computational Chemistry Data

TPSA 40.54
LogP -0.9331
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Fatty chain compounds

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2-Hydroxy-N,N-dimethylacetamide

CAS No. 14658-93-6

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