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Structure of 147081-59-2
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tert-Butyl (3S)-3-(methylamino)pyrrolidine-1-carboxylate is a stereochemically defined, bench-stable building block featuring a chiral pyrrolidine core with a methylamino substituent. This protected amine moiety enables straightforward incorporation into complex molecular architectures, particularly in the synthesis of bioactive alkaloids and pharmaceutical intermediates. The tert-butyl ester group facilitates selective deprotection under mild acidic conditions, streamlining downstream functionalization.
tert-Butyl (3S)-3-(methylamino)pyrrolidine-1-carboxylate serves as a versatile chiral building block for the synthesis of bioactive nitrogen-containing heterocycles. The (3S)-configured pyrrolidine core enables stereoselective transformations, while the tert-butoxycarbonyl (Boc) group provides robust protection for primary amines under standard reaction conditions. The methylamino substituent offers a handle for further functionalization via alkylation or reductive amination, and the molecule exhibits excellent bench stability, ease of purification, and compatibility with diverse coupling and cyclization protocols in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: