I-bu-rG Phosphoramidite

Name: I-bu-rG Phosphoramidite
Brand: ChemScene
Availability: InStock
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CAS No. 147201-04-5
Cat. No. CS-W006103
Purity≥96%
MDL No.MFCD00080299

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Structure of 147201-04-5

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Description

Heptafluorobutyric anhydride is a perfluoroacylated acylation reagent, that forms stable, volatile derivatives with alcohols, amines, and phenols. It is majorly used to prepare electron-capturing derivatives for GC/electron capture detection. It is generally used with an acid scavenger, to help drive the reaction to completion and to prevent column damage from acidic by-products of the derivatization reaction. It is also used for the frequent testing of drugs of abuse such as, amphetamines and phencyclidine by GC-MS technique.Learn more in the Product Information

Application

I-bu-rG Phosphoramidite serves as a key building block for the synthesis of oligonucleotide sequences containing guanine derivatives, enabling efficient incorporation during solid-phase synthesis. Its sterically hindered isobutyl group enhances stability and reduces side reactions, while maintaining high coupling efficiency. The phosphoramidite functions reliably in standard DNA/RNA synthesis protocols, offering excellent yield and purity for research-scale applications.

General Information

CAS No. 147201-04-5
Cat. No. CS-W006103
Purity ≥96%
MDL No. MFCD00080299
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅₀H₆₈N₇O₉PSi
Molecular Weight 970.18
Synonym(s) None
SMILES COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N5C(N=C(NC(C(C)C)=O)NC6=O)=C6N=C5)O4

Computational Chemistry Data

TPSA 184.31
LogP 9.68898
H_Acceptors 14
H_Donors 2
Rotatable_Bonds 21

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Life Science Nucleosides & Nucleotides Halogen-modified Nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

Catalysis Compounds by Element Classes Metal Compounds Semimetal Compounds

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I-bu-rG Phosphoramidite

CAS No. 147201-04-5

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