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CS-W001157 4
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Rac-(1s,4s)-4-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis

  • CAS No. 147900-45-6

  • Cat. No. CS-0217005
  • Purity≥98%
  • MDL No.None
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

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Rac-(1s,4s)-4-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis|CS-0217005

Structure of 147900-45-6

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Description

Rac-(1s,4s)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis features a sterically hindered cyclohexane scaffold with a fluorenylmethoxycarbonyl-protected amine. This configuration enables efficient incorporation into peptide synthesis workflows under standard conditions, delivering robust coupling efficiency and high stability during storage.

Application

Rac-(1s,4s)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis serves as a robust chiral building block for peptide synthesis and medicinal chemistry applications. The Fmoc-protected amino group enables efficient coupling under standard conditions, while the rigid cyclohexane scaffold provides defined stereochemistry and conformational stability. This compound exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in diverse coupling protocols.

General Information

  • CAS No. 147900-45-6
  • Cat. No. CS-0217005
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₃NO₄
  • Molecular Weight 365.42
  • Synonym(s) cis-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclohexanecarboxylic acid
  • SMILES O=C(O)[C@@H]1CC[C@@H](CC1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O

Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.1685
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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