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CS-W001157 4
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Rac-(1s,4s)-4-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis

  • CAS No. 147900-45-6

  • Cat. No. CS-0217005
  • Molecule weight365.42
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Rac-(1s,4s)-4-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis|CS-0217005

Structure of 147900-45-6

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General Information

  • CAS No. 147900-45-6
  • Cat. No. CS-0217005
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₃NO₄
  • Molecular Weight 365.42
  • Synonym(s) cis-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclohexanecarboxylic acid
  • SMILES O=C(O)[C@@H]1CC[C@@H](CC1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O

Description

Rac-(1s,4s)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis features a sterically hindered cyclohexane scaffold with a fluorenylmethoxycarbonyl-protected amine. This configuration enables efficient incorporation into peptide synthesis workflows under standard conditions, delivering robust coupling efficiency and high stability during storage.

Application

Rac-(1s,4s)-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexane-1-carboxylic acid, cis serves as a robust chiral building block for peptide synthesis and medicinal chemistry applications. The Fmoc-protected amino group enables efficient coupling under standard conditions, while the rigid cyclohexane scaffold provides defined stereochemistry and conformational stability. This compound exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in diverse coupling protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.1685
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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