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Structure of 1480547-81-6
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4-Bromo-3-fluoro-N-(thiophen-2-ylmethyl)aniline features a strategically positioned bromo and fluoro substituent on the aromatic ring, enhancing electronic modulation and enabling selective coupling reactions. The thiophen-2-ylmethyl group provides a robust, electron-donating handle for further functionalization in cross-coupling and medicinal chemistry applications.
4-Bromo-3-fluoro-N-(thiophen-2-ylmethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its ortho-halogenated aniline core facilitates palladium-catalyzed cross-coupling reactions, while the thiophene-containing amine functionality provides orthogonal reactivity and enhanced solubility. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.
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Lot numbers can be found on the outside label of a product: